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The gastrointestinal tract of vertebrate species contains melatonin, which participates in several physiological functions. Some of these effects are mediated via specific membrane receptors (MT 1 and MT 2 ). In the present study, the distribution of the MT 2 receptor protein in the gastrointestinal tract was localized, and changes in MT 2 receptor density were observed...
Thrombomodulin (TM) contributes to the inactivation of thrombin which activates proteinC, a major anticoagulant and anti-inflammatory protein. This report describes the distribution and localization of TM in the rat duodenum by light and electron microscopic immunohistochemistry. In addition to the endothelium of the entire vasculature, TM was found on the non-vascular structures, cellular networks...
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