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Sunitinib is a multitargeted kinase inhibitor that inhibits many receptor tyrosine kinases and has been used in the treatment of gastrointestinal stromal tumors, metastatic renal cell carcinoma, and pancreatic neuroendocrine tumors. In this study, the effects of sunitinib given to rats, both alone and after stress with cisplatin, were investigated. The animals were divided into four groups – (1) control...
The chemotherapeutic cisplatin, which is widely used in many cancer types, causes testicular toxicity. Sinapic acid has many therapeutic effects such as antioxidant, anti‐inflammatory and antihyperglycaemic. This study aimed to investigate the improving effects of sinapic acid in cisplatin‐induced testicular toxicity. Twenty‐eight rats were distributed into 4 groups. Control group: saline was applied...