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Philips has introduced the world's first whole body sequential PET/MR system. We present the current status of MR-based attenuation correction (MRAC) technique. MRAC consists of MR image acquisition, segmentation, truncation compensation (TC), μ-value assignment, as well as correction for patient table and RF coils. These components have been described last year; this paper focuses on updates of the...
Three-dimensional serial section imaging delivers high spatial resolution and histological detail, which facilitates analysis of differentiation and development by exact labelling of tissues and cells, unknown to other 3-D imaging modalities. We propose an algorithm for interleaved reconstruction and segmentation of tissues in serial section volumes by diffusion-based registration and adaption of...
This paper presents a 3D non-rigid registration algorithm between histological and MR images of the prostate with cancer. To compensate for the loss of 3D integrity in the histology sectioning process, series of 2D histological slices are first reconstructed into a 3D histological volume. After that, the 3D histology-MRI registration is obtained by maximizing a) landmark similarity and b) cancer region...
This paper introduces a new method for automatic quantification of subcutaneous, visceral and non-visceral internal fat from MR-images acquired using the two point Dixon technique in the abdominal region. The method includes (1) a three dimensional phase unwrapping to provide water and fat images, (2) an image intensity inhomogeneity correction, and (3) a morphon based registration and segmentation...
We present two methods for automatic registration of microscope images of consecutive tissue sections. They represent two possibilities for the first step in the 3-D reconstruction of histological structures from serially sectioned tissue blocks. The goal is to accurately align the sections in order to place every relevant shape contained in each image in front of its corresponding shape in the following...
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