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Congenital heart disease (CHD) is the most common type of birth defect. It is suspected that polymorphisms in folate metabolism are associated with an increased risk of CHD, but the conclusion remains unclear. Studies have reported that the MTHFR C677T polymorphism was associated with the development of structural congenital heart malformations. The objective of this study was to conduct a...
Die Suszeptibilität komplex-genetischer Erkrankungen wird durch eine unbekannte Anzahl genetischer Faktoren bestimmt. In den letzten Jahrzehnten sind Hunderte von Suszeptibilitätsloci für die Alzheimer-Krankheit (AD), das idiopathische Parkinson-Syndrom (PD), Schizophrenie (SZ) und multiple Sklerose (MS) beschrieben worden. Diese schwierig zu überschauende Datenlage für jede dieser Erkrankungen wird...
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