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The specific aim of this study was to investigate the pharmacokinetic parameters of antibiotics represented by vancomycin and amikacin in the subeschar tissue fluid (STF) in patients with early stage severe burn. Twenty patients were studied: age 30.7±8.0 years old, weight 60.6±8.4kg, total burn surface area (TBSA) 68.39±17.85%, creatinine clearance (CCr) 95.45±23.14ml/min, mean±S.D. Patients received...
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