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The article is about induction of apoptosis in human hepatoma HepG2 cells by myricetin (MYR). The human hepatoma HepG2 cells was treated with different doses myricetin for 72 h. Cytotoxicity was evaluated by SRB assay, apoptosis-related alterations in morphology ascertained by cytochemical staining(Hoechst 33258) and transmission electron microscopy (TEM). The cell cycle and apoptotic rate were quantified...
Objectives: To compare anti-tumor activities of different extracts from the medicinal plants Pinellia ternata and its allied species.Methods: MTT cell proliferation assay was used to evaluate the cytotoxicity of the extracts on Bel-7402, HT-29, Hela cells. FCM assay and DNA fragmentation analysis were used to detect cell apoptosis. Immunohistochemical SABC method was performed for detection of the...
Paclitaxel is an anticancer agent often used in clinical oncology practice. Polymeric capsules represent an effective tool for the encapsulation and smart release of different compounds. Paclitaxel was loaded into the capsules, fabricated by means of the layer-by-layer assembly of oppositely charged polyelectrolytes. The effective encapsulation of paclitaxel was demonstrated and its release was characterized...
Before using semiconductor quantum dots (QDs) in biomedical applications in vivo, it's important to know about their interaction with biological surroundings, stability in living organisms, intracellular distribution and cytotoxicity. We have investigated CdTe-MPA and (CdSe)ZnS-MUA QDs in the osteosarcoma U2-OS cell culture. The changes in photoluminescence spectra of QDs, the localization of QDs...
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