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The efficiency research about protein sub-cellular localization has become a hot topic recently. Feature extraction plays an important role in the accurate classification or location of proteins. Since the contribution of each feature dimension is different, this paper enlarges the contribution of feature dimensions which have great effect on classification by weighting with its Fisher linear discriminant...
Physical interactions between the proteins in a living organism helps in identification of most protein-protein interaction data. The annotated proteins are previously known by their functions. Their knowledge is definite. The un-annotated proteins are annotated based on estimation of such similar functions. Generally a cluster containing annotated nodes with their adjacent unlabeled nodes is assumed...
In the protein-protein interactions (PPI), hot regions are the key factor to maintain metabolism and the cause of disease. The conformation and prediction of the hot regions effectively is a worth researching topics. This paper proposes a prediction method of hot regions based on complex network and community detection. In the prediction process, a hotspots retrieving strategy is used to exploit false...
The aim of this paper is to investigate the potential of Visible and short-wave near-infrared spectroscopy (Vis/SWNIR) technique used for brand discrimination of milk powder. Fifty samples for each brand were studied. Based on the independent components (ICs) as the input variable obtained from fast fixed-point independent component analysis (FastICA), Least-squares Support Vector Machine (LS-SVM)...
Thresholding is always critical and decisive in problem solving. In this paper, we propose an adaptive fuzzy logic-based approach to thresholding for exon prediction problem, which is an important problem in bioinformatics. Rather than using the same threshold for the entire dataset, we allow the thresholds to vary along the dataset based on the local statistical properties. We incorporate it in a...
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