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In recent years, numerous protein-protein interaction (PPI) datasets have been generated with the development of high-throughput experimental techniques. These datasets enable researchers to uncover protein complexes on network level. However, the performance of the computational methods relies heavily on the quality of the underlying protein interaction data, and these datasets are usually quite...
In order to overcome the limitations of global modularity and the deficiency of local modularity, we introduce a hybrid modularity measure LGQ (Local-Global Quantification) which adopts a suitable modularity adjustable parameter to control the balance of global detecting capability and local search capability in Protein-Protein Interaction (PPI) network. On the other hand, a new protein complex mining...
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