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Dissolved oxygen (DO) is an important parameter with significant effect on cellular development and function. Micron-scale laminar flow and hydrodynamic focusing provide ideal tools for the generation of controlled chemical micro-environments and their application as stimuli to cells. In this paper, we demonstrate the generation and characterization of multistream laminar flow and hydrodynamically...
In this paper, we report on an on-chip separation device that is based on guided dielectrophoresis (DEP). The simple design comprises a pair of electrodes and a microfluidic channel for sample delivery. Continuous separation into two distinct populations (corresponding to positive and negative DEP, respectively) in the microchannel was achieved without the need of accurate hydrodynamic focusing or...
Discrete micro-droplet has the huge advantage in microfluidic applications. More flexible manners to manipulate droplet are desired. In this paper, a platform is constructed for droplet manipulation by directing the motion of water-in-oil droplets passively with micro-pillar array. These pillars are embedded inside a microchannel with very low aspect ratio. The pillars are arranged to set up a barrier...
In this paper, we propose a microfluidic chip to generate well-defined microcapsule. In order to make core-shell microcapsule, a simple design capable of 3-dimensional hydrodynamic focusing was embedded in the proposed microfluidic chip. Cell suspension is focused 3-dimensional hydrodynamic in microchannel by the hillock based geometries, and then the core-shell structure of alginate microcapsules...
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