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Progress in the field of prosthetic cardiovascular devices has significantly contributed to the rapid advancements in cardiac therapy during the last four decades. The concept of mechanical circulatory assistance was established with the first successful clinical use of heart–lung machines for cardiopulmonary bypass. Since then a variety of devices have been developed to replace or assist diseased...
The goal of the present study was to develop a physiologically realistic 3D computational fluid dynamics (CFD) model of the left coronary artery under normal and disease conditions to estimate blood flow induced shear stress, and then use the computed shear stress to stimulate vascular endothelial cells in vitro. A 3D geometry of the left coronary artery was built in ProE and the CFD analysis of the...
The CFD (Computational Fluid Dynamic) technology was used to investigate the air movement characteristic and aerosol deposition in the human upper respiratory tract. Steady and cyclic respiratory with the breathing intensity of Q = 30 L/min and aerosol diameter of d = 0.3, 6.5 mum were considered. Experimentally validated computational fluid-aerosol dynamics results showed the following: the phenomenon...
Methods of Computational Fluid Dynamics are applied to simulate pulsatile blood flow in human vessels and in the aortic arch. The non-Newtonian behaviour of the human blood is investigated in simple vessels of actual size. Turbulence effects are taken into account. A detailed time-dependent mathematical convergence test has been carried out. The realistic pulsatile flow is used in all simulations...
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