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AimsCerebral amyloid angiopathy (CAA) represents the deposition of amyloid β protein (Aβ) in the meningeal and intracerebral vessels. It is often observed as an accompanying lesion of Alzheimer's disease (AD) or in the brain of elderly individuals even in the absence of dementia. CAA is largely age‐dependent. In subjects with severe CAA a higher frequency of vascular lesions has been reported. The...
To better understand the characteristics of amyloid deposition in the choroid plexus, we examined autopsied brain by routine histology, immunohistochemistry, and electron microscopy in three group of patients: primary systemic amyloidosis (n=7), cerebral amyloid angiopathy (CAA, n=6), and controls (n=3). Three of the CAA patients had Alzheimer's disease. Congophilic, birefringent amyloid deposits...
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