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MicroRNAs are short regulatory RNAs which play a major role in regulating gene expression. In this study, we employed bioinformatics techniques to predict microRNA target sites for interleukin-17 family. We aimed at identifying the pattern of microRNA regulatory mechanism on interleukin-17 family. This study provides insight into the expression pattern of interleukin-17 family in controlling immunopathologic...
MicroRNAs (miRNAs) are small noncoding RNAs which regulate gene expression. In this research, we used the Multiz alignments data of 44 Vertebrates to retrieve syntenic homolog sequences. And we identified 37 members of miR-1302 family among 71 potential homolog sequences. Then we analyzed the 37 homologs of hsa-mir-1302s by RepeatMasker and found all of these sequences are derived from MER53 elements...
For almost three decades, cancer was thought to result from changes in the structure and/or expression of protein coding genes. The discovery of thousands of genes that produce noncoding RNA (ncRNA) transcripts in the past few years suggested that the molecular biology of cancer is much more complex. MicroRNAs (miRNAs), an important group of ncRNAs, have recently been associated with tumorigenesis...
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