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Objectives: The inaccurate implantation of deep brain stimulation electrode could cause in-effective therapy and varied side-effects. This study aims to intra-operatively localise the subthalamic nucleus (STN) using voluntary movement related local field potentials (LFPs) to improve the electrode implantation accuracy. Methods: STN LFPs were recorded during auditory cued clicking motor task in twelve...
Understanding the relationship between neural activity in motor cortex and muscle activity during movements is important both for basic science and for the design of neural prostheses. While there has been significant work in decoding muscle EMG from neural data, decoders often require many parameters which make the analysis susceptible to overfitting, which reduces generalizability and makes the...
The role that neurons in the motor and premotor cortical regions have in facilitating muscle activation during reaching and grasping tasks can be detected through cross-correlative techniques such as spike triggered averaging (SpTA). The use of chronically implanted electrodes can provide information regarding the dynamics of this functional role over time. Using chronically implanted microwire arrays...
Nowadays, the man-machine interfaces are becoming more important in our interaction with robotic systems. One particular case is on prosthetic devices, where the need of "biofeedback" is of vital importance to achieve subconscious control of these devices. In order to provide this feedback, so the device can be included into the user's body image, we use electrical stimulation as a substitute...
The implementation of an effective approach to restore the link between the nervous system and artificial devices in disabled subjects is crucial to increase the acceptability and usability of these systems. Among the different possible solutions, the development of invasive cortical neural prostheses (ICNPs) is very appealing because of the possibility of extracting information on the user's intention...
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