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Musculoskeletal disorders (MSDs) account for the largest fraction of temporary and permanent disabilities. Osteoarthritis (OA) is one of the most common MSDs which is characterized by a degeneration of articular cartilages. Understanding and preventing OA are of paramount importance in our aging yet very active society, and in this context, computer-assisted models of articulations are highly demanded...
The human mesenchymal stem cells can differentiate into cardiomyocytes, osteoblasts, chondroblasts, adipocytes, endothelial, hepatocyte and neuron cells, when hMSCs are exposed to certain physical and chemical stimulants. It is hoped that the differentiation of hMSCs into certain cell types in certain in-vitro conditions can provide for treatment of the certain disease and pathologic situation. The...
The deformations of the neck and head of the human dried femur were measured and analyzed with loads applied at the femoral head. Particular attention was paid to measurements of bones with osteoporosis. We used double exposures or real-time holographic interferometry to measure precisely. The distal part of each femur was embedded in super hard plaster, and the load was applied at the femoral head...
Skeletal deformity is an important characteristic of osteogenesis imperfecta (OI). To study the influence of deformity in stress/strain distribution, a finite element analysis (TEA) of the femur during physiological loading was developed. The diaphysis was altered mathematically to reflect different clinical deformities of OI. Joint reaction and muscle forces were adapted from the literature to reproduce...
This paper discusses the development of a system to measure continuous cardiac baroreceptor measurement during a 45-minute 70-degree head-up tilt (HUT) of five groups of subjects suffering the following: chronic fatigue syndrome (CFS), CFS with fibromyalgia (CFS-FM), CFS with postural orthostatic tachycardia syndrome (CFS-POTS), controls with POTS (CON-POTS), and controls (CON). The duration of the...
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