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Background
Sleep disorders are prevalent among patients with Alzheimer's disease (AD), and the APOE ε4 genotype is a key genetic risk factor for sporadic AD. However, the combined effect of the genotype and sleep disorders on cognitive decline remains uncertain.
Methods
A total of 972 participants were drawn from the SILCODE cohort, comprising 655 without the ε4 allele (APOE−) and 317 with ε4 allele...