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Despite the widespread application of microarray imaging for biomedical research, barriers still exist regarding its reliability and reproducibility for clinical use. A critical problem lies in accurate spot segmentation and quantification of gene expression level (mRNA) from microarray images. A variety of commercial and research freeware packages are available, but most cannot handle array spots...
This paper proposes a Fuzzy System learned through Fuzzy Clustering and Support Vector Machine (FS-FCSVM). The FS-FCSVM is a fuzzy system constructed by fuzzy if-then rules with fuzzy singletons in the consequence. The structure of FS-FCSVM is constructed by fuzzy clustering on the input data, which helps to reduce the number of rules. Parameters in FS-FCSVM are learned through a support vector machine...
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