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A novel truncated form of Bcl-2, termed Bcl-2ψ, was discovered in invasive prostate cancer cells, using laser capture microdissection, RNA-polymerase cycling reaction, and microarray analysis. The expression of Bcl-2ψ increased prior to metastasis in higher-grade prostate cancer. The immunoreactive Bcl-2ψ was specifically identified in higher-grade prostate cancer cells. These findings suggest that...
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