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Biologically active compounds are considered as powerful food factors that elicit profound effects on the maintenance of human health, and disease prevention. The research into how bioactive compounds work and their role in disease prevention in vitro and in vivo is rapidly expanding. Carotenoids are one among several classes of biologically active compounds that have been reported to possess greater...
As part of a continuing search for potential anticancer drug candidates, 1-benzyl-3-(5-hydroxymethyl-2-furyl)indazole (YC-1) was evaluated in the Japanese Cancer Institute's (JCI) in vitro disease-oriented anticancer screen. The results indicated that YC-1 showed impressive selective toxicity against the NCI-H226 cell line. Therefore, the molecular mechanism by which YC-1 affects NCI-H226 cell growth...
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