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Transforming growth factor beta-1 (TGFβ-1) and tumor necrosis factor alpha (TNF-α), an activator of nuclear factor kappa B (NF-κB), modulate apoptosis and/or cell growth. This study was designed to investigate the activity of NF-κB and its regulation of inhibitor of apoptosis gene (c-IAP2) in two human prostate cancer cell lines, DU-145 (which is androgen unresponsive) and ALVA-101 (which is moderately...
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