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We investigated the modifications in endogenous antioxidant capacity and oxidative damage in the brain, liver, kidney and testis in mice exposed to bisphenol A (BPA), an environmental endocrine disrupter. Mice were exposed to BPA throughout embryonic/fetal life and during lactation by feeding their pregnant/lactating mothers BPA at 5 or 10 μg per milliliter of drinking water. At the age of four weeks,...
In this study, the early nephrotoxic potential of mercuric chloride (HgCl 2 ) has been evaluated in vitro, by exposing a renal-derived cell system, the tubular epithelial Madin-Darby canine kidney (MDCK) cell line, to the presence of increasing HgCl 2 concentrations (0.1-100 μm) for different periods of time (from 4 to 72 h). As possible biological markers of the tubular-specific toxicity...
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