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This study was undertaken to determine theeffect of 5-fluorouracil on gastrointestinalcarcinogenesis. Sixty rats were divided into threegroups of 20 rats each. All rats were exposed toN-methyl-N′-nitro-N-nitrosoguanidine for the first20 weeks. Group 1 rats received intraperitonealinjections of 5-fluorouracil for the first 20 weeks andwere then observed for the second 20 weeks. Group 2 ratsalso received...
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