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We prospectively evaluated the association of tumor response with change of quality of life (QOL) in patients with advanced gastrointestinal tumors receiving palliative chemotherapy. Out of 133 eligible patients, 90 (68%) completed the European Organization for Research and Treatment Quality of Life Questionnaire C-30 (EORTC QLQ C-30) at baseline and at regular intervals during palliative chemotherapy...
Background:Recurrent glioblastoma multiforme (GBM) is resistantto most therapeutic endeavors, with low response rates and survival rarelyexceeding six months. There are no clearly established chemotherapeuticregimens and the aim of treatment is palliation with improvement in thequality of life. Patients and methods:We report an open-label, uncontrolled,multicenter phase II trial of temozolomide...
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