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We propose in this paper a new fully integrated CMOS interface dedicated for cells manipulation and separation in LoC devices. The proposed interface includes all microelectronics circuits for dielectrophoretic manipulation and capacitive detection. It contains also an embedded frequency and phase micro controller to ensure several kinds of cells displacements such as rotation, translation and separation...
We describe in this paper cells sensing and manipulation methods, as well as platforms based on Lab-on-chip devices. Among other contributions, new circuit and microfluidic techniques, and packaging methods are proposed for efficient cells manipulation and detection. The proposed devices include high-sensitivity sensing circuits (200 mV/fF), low-pressure liquid injection interfaces (<;;0.65 psi),...
We report on the development of a feedback control system that utilizes a custom CMOS optical sensor, to facilitate controlled and precise dispensing and transport of nano-liter liquid sample droplets by leveraging liquid-DEP (L-DEP) and droplet-DEP (D-DEP) actuation schemes. Operationally, L-DEP and D-DEP typically require application of AC voltages across a pair of coplanar microelectrodes for a...
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