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The characterization of a 10×10-SPAD detector module fabricated in a 0.35µm High Voltage CMOS technology is presented. The detector is designed to find application in Fluorescence Lifetime spectroscopy and is capable of performing lifetime measurement by using the time-gated technique. The characterization explores the dark count distribution, the detector dynamic range and the gating performances...
The first label-free LEAC biosensor immunoassay demonstration is reported. CMOS chips with integrated photoconductor arrays detected 150 kDa tuberculosis related antibodies and 18 kDa protein antigens. The limit of detection for thickness change was 120 pm.
We describe a two-chip micro-scale time-resolved fluorescence analyzer integrating excitation, detection and filtering. A new 8 ?? 8 array of drivers integrated in standard low-voltage 0.35 ??m CMOS is bump-bonded to AlInGaN blue micro-pixellated light-emitting diodes (micro-LED). The array is capable of producing sample excitation pulses with a width of 777 ps (FWHM) enabling short lifetime fluorophores...
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