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miRNAs are small regulators that mediate gene expression and each miRNA regulates specific target genes. In animals, target prediction of the miRNAs is accomplished through several computational methods, i.e. miRanda, TargetScan and PicTar. Typically, these methods predict targets from features of miRNA-target interaction such as sequence complementarity, free energy of RNA duplexes and conservation...
Many feature selection methods have been proposed and most of them are in the supervised learning paradigm. Recently unsupervised feature selection has attracted a lot of attention especially in bioinformatics and text mining. So far, supervised feature selection and unsupervised feature selection method are studied and developed separately. A subset selected by a supervised feature selection method...
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