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This paper reports a novel bioMEMS device that integrates mechanical constriction for single cell trap in the channels, which are enclosed by thick (or 3D) C-PDMS (carbon-black-PDMS) electrodes and bottom planar transparent electrode for dielectrophoretic (DEP) cell manipulation. Leveraging hydrodynamics and dieletrophoresis, this simple biomedical microsystem enables more efficient loading of one...
This study is focused on electroosmetic micromixer and the effects of driving force are investigated in the sense of different mixing channel width schemes. Two pairs of electrodes are mounted on the sidewalls of mixing channel to provide the required electric field. Various Numerical simulations are performed to assess the fluid flow in the presence of the electrokinetic driving force. Throughout...
This paper presents the design, simulation and fabrication of dielectrophoretic chip with integrated nickel 3D electrodes for bioparticle separation. Finite element analysis software COMSOL Multyphysics 4.3 is used to measure the electric field distribution and also the temperature profile inside the microfluidic channel. The temperature rise is found to be 0.5 K. Electric field distribution shows...
Microorifice-based fusion makes use of electric field constriction to assure high-yield one-to-one fusion of selected cell pairs. The aim of this paper is to verify feasibility of high-yield cell fusion on a microfluidic chip. This paper also examines viability of the fusant created on the chip. We fabricated a microfluidic chip to fuse selected cell pairs and to study postfusion behavior. We used...
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