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PurposeTo investigate the combined use of hyperoxia‐induced ΔR2* and ΔR1 as a noninvasive imaging biomarker of tumor hypoxia.
Materials and MethodsMRI was performed on rat GH3 prolactinomas (n = 6) and human PC3 prostate xenografts (n = 6) propagated in nude mice. multiple gradient echo and inversion recovery truefisp images were acquired from identical transverse slices to quantify tumor R2* and...
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