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Natural Killer (NK) cells play a significant role in the early defense against virus infections and cancer. Recent studies have demonstrated the involvement of NK cells in both the induction and effector phases of vaccine‐induced immunity in various contexts. However, their role in shaping immune responses following SARS‐CoV‐2 vaccination remains poorly understood. To address this matter, we conducted...
Various vaccines have been challenged by SARS‐CoV‐2 variants. Here, we reported a yeast‐derived recombinant bivalent vaccine (Bivalent wild‐type [Wt]+De) based on the wt and Delta receptor‐binding domain (RBD). Yeast derived RBD proteins based on the wt and Delta mutant were used as the prime vaccine. It was found that, in the presence of aluminium hydroxide (Alum) and unmethylated CpG‐oligodeoxynucleotides...