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The purpose of this study was to determine the disease-free and overall survival (DFS and OS, respectively) in 991 postgastrectomy gastric cancer patients untreated (n = 372) or treated with either oxaliplatin-based (n = 376) or docetaxel-based (n = 243) chemotherapy and to identify prognostic factors that could help establish subgroups of patients who would benefit from such treatment. The median...
Colon cancers do not represent a homogeneous entity, and the two main known pathways are the microsatellite instability (MSI) and chromosomal instability pathways. Although statistically significant, the absolute improvement in overall survival with 5-fluorouracil (5-FU) adjuvant chemotherapy in patients with stage II colon cancer is small and does not support the use of adjuvant chemotherapy in all...
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