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To evaluate the role of pegylated liposomal doxorubicin with low-dose metronomic cyclophosphamide as primary systemic treatment in locally advanced breast cancer.The activity and safety of intravenous pegylated liposomal doxorubicin 20 mg sqm −1 biweekly for eight courses in combination with metronomic cyclophosphamide 50 mg day −1 orally were evaluated in 29 patients with locally...
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