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Radiofrequency ablation has been used to treat some types of cardiac arrhythmias. We have previously proposed an ARMAX model (non structural) to estimate the temperature in the tissue during ablation. Computer modeling has allowed us to study the temperature distribution by means of solving numerically theoretical models based on partial differential equations, which represent physical phenomena....
The foreign body reaction that the neural tissue develops around an implanted electrode contributes to insulate the probe and enhances the electrical and mechanical mismatch. It is a complex interaction among cells and soluble mediators and the knowledge of this phenomenon can benefits of formal and analytical methods that characterize the mathematical models. This work offers a lumped component model,...
Sensing neural activity within mechanically active tissues poses particular hurdles because most electrodes are much stiffer than biological tissues. As the tissue deforms, the rigid electrodes may damage the surrounding tissue. The problem is exacerbated when sensing neural activity in experimental models of traumatic brain injury (TBI) which is caused by the rapid and large deformation of brain...
This paper demonstrates the electromagnetic modeling and simulation of an implanted Medtronic deep brain stimulation (DBS) electrode using finite difference time domain (FDTD). The model is developed using Empire XCcel and represents the electrode surrounded with brain tissue assuming homogenous and isotropic medium. The model is created to study the parameters influencing the electric field distribution...
Mathematical model of homogeneous cardiac tissue is used to show that externally applied current can create changes of transmembrane potential in long distances from stimulating electrodes.
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