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Neual chips have been used to detect and modulate neuroelectrical activity for almost 30 years. Their capability of simultaneous, multi-site recording enable neuroscientists to study neural signal processing through neural circuits. By improving sensitivity and spatial resolution, nano scale neural chips may revolutionize neural detection and modulation at cellular and molecular levels. We developed...
Piezoelectric quartz crystal impedance (PQCI) analysis was applied to study the binding of L-tryptophan to human serum albumin (HSA), which was immobilized on the matrix of bare gold elelctrode/chitosan/glutaraldehyde/cysteamine/nanogold particles to maintain biocompatibility, increase capacity and allow renewing the electrode. The real-time course of the resonant frequency and equivalent circuit...
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