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Clinical treatment of psoriasis remains challenging because of possible long‐term drug toxicities and loss of therapeutic effects over time. CX‐5461 is a novel selective inhibitor of RNA polymerase I. Our previous studies have shown that CX‐5461 has potent anti‐inflammatory effects. Here we investigated whether CX‐5461 could inhibit the development of imiquimod‐induced experimental psoriasis in mice...
This systematic review and meta‐analysis of randomized controlled trials (RCTs) examined the topical use of multi‐herbal formulations for the management of psoriasis vulgaris. Studies were identified from PubMed, Cochrane library, EMBASE, and the Chinese databases CNKI and CQVIP. Methods were according to the Cochrane Handbook and meta‐analyses used RevMan 5.1. Nine studies met the inclusion/exclusion...
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