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Immunothrombosis, an inflammation‐dependent activation of the coagulation cascade, leads to microthrombi formations in small vessels. It is a dreaded complication of COVID‐19 and a major cause of respiratory failure. Due to their size and disseminated nature, microthrombi are currently undetectable. Here, noninvasive detection of a volatile reporter in the exhaled air is introduced for assessment...
Immunothrombosis
Thrombin's enzymatic activity in the living organism was for the first time measured in the exhaled breath. Novel nanoprobes released a gaseous reporter in potentially fatal microthrombi. This technology aims to improve precision of care in serious conditions including sepsis, COVID‐19, diabetes complications, and lung fibrosis. More details can be found in article number 2304903...
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