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It has previously been reported that exposure to repeated restraint stress induces hyperalgesia in male rats, an effect that was not observed in females. The aim of the present study was to investigate the effects of chronic variable stress over 40days on nociception threshold indexed by tail-flick latency in male and female adult rats. The results showed different behavior in chronically stressed...
Gamaro, G. D., M. H. Xavier, J. D. Denardin, J. A. Pilger, D. R. Ely, M. B. C. Ferreira, C. Dalmaz. The effects of acute and repeated restraint stress on the nociceptive response in rats. Physiol Behav 63(4) 693-697, 1998. The effects of acute and repeated restraint stress on nociception, as measured by the tail-flick latency, were studied in adult male and female rats. After the exposure to a single...
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