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Our knowledge of the pharmacogenetics of warfarin and clopidogrel continues to expand as we learn more about the individual genetic variations that contribute to the drugs’ efficacy and toxicity. We aim to review the recent developments in the field and discuss the clinical implications for the treatment of ischemic stroke patients. Despite recent advances, there is still insufficient data to suggest...
Résumé: Les cancérologues se heurtent toujours aux deux écueils majeurs de la chimiothérapie, la résistance tumorale, en grande partie liée au fait que les traitements sont décidés sur des critères statistiques d’efficacité, et la toxicité, souvent sévère, due à l’index thérapeutique étroit de tous les médicaments anticancéreux. De nouvelles approches sont nécessaires pour individualiser les traitements...
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