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In Synthetic Biology, the idea of using feedback control for the mitigation of perturbations to gene regulatory networks due to disease and environmental disturbances is gaining popularity. To facilitate the design of such synthetic control circuits, a suitable model that captures the relevant dynamics of the gene regulatory network is essential. Traditionally, Michaelis-Menten models with Hill-type...
In order to function reliably, synthetic molecular circuits require mechanisms that allow them to adapt to environmental disturbances. Least mean squares (LMS) schemes, such as commonly encountered in signal processing and control, provide a powerful means to accomplish that goal. In this paper we show how the traditional LMS algorithm can be implemented at the molecular level using only a few elementary...
The applications of infection models like the Linear Threshold or the Domingos-Richardson model requires a graph weighted with infection probabilities. In many real-life applications these probabilities are unknown; therefore a systematic method for the estimation of these probabilities is required. One of the methods proposed to solve this problem, the Inverse Infection Model, was originally formulated...
In this paper, we propose models for single and coupled on-chip global interconnect lines by distributed RLGC parameters using state space approach. Models for single and coupled lines are validated by comparing with SPICE simulations. Interconnect performance metrics are obtained from the proposed models for 65 nm, 90 nm, 130 nm and 180 nm technology nodes based on PTM values. In case of coupled...
One of the most important issues in electrical modeling of physiological system is to find an effective way of making the most accurate equivalent electrical circuit. For this reason, in this research a new way of calculation of equivalent resistance of any type of vessels in biological systems has been proposed. The research presented in this paper is part of an ongoing effort to utilize mathematical...
Power quality interference sources generate a large number of harmonics and negative-sequence current into power grid in the process of using electricity. Harmonics and negative-sequence current not only affect power grid's safety and economical operation also cause interference to other normal users, which brings large threat and danger to the power grid and users. As an effective method to prevent...
The core of establishment of enterprise alliance is the profit allocation of the member, and enterprise alliance is the result of group decision-making of all members. The paper advances a method combined with Shapley value and group decision-making model to solute the problem that how to get the function of enterprise alliance in Shapley value model. On the basis of these, the solution of model is...
For several decades, the output from semiconductor manufacturers has been high volume products with process optimisation being continued throughout the lifetime of the product to ensure a satisfactory yield. However, product lifetimes are continually shrinking to keep pace with market demands. Furthermore there is an increase in dasiafoundrypsila business where product volumes are low; consequently...
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