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Previous studies from our laboratory showed that anxiety-related responses induced by nicotine (NIC), measured by the elevated plus maze, were abolished by 2-OH-saclofen (GABA B receptor antagonist) (1 mg/kg; ip) or the lack of GABA B receptors (GABA B1 knockout mice). Based on these behavioral data, the aims of the present study were: 1) to evaluate the possible neurochemical...
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