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The repair of articular cartilage has posed a longstanding orthopedic challenge. The concept of marrow stimulation is basically the intentional injury of a subchondral bone below a cartilage lesion to elicit a wound repair response. However, the desire to fill the lesion with a blood clot is at odds with platelet-driven clot retraction, which results in clot shrinkage and detachment. Therefore, BST-CarGel...
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