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AimsA recent study examining the specificity of human epidermal growth factor receptor (HER) 2 pharmacodiagnostic antibodies demonstrated that CB11 and 4B5 stain both HER2‐transfected and HER4‐transfected cell lines. However, there has been no evidence showing that 4B5 has affinity for HER4 in clinically obtained tissues, and, if so, whether this has any impact on the assessment of HER2. We therefore...
Lee A H S, Key H P, Bell J A, Hodi Z & Ellis I O (2012) Histopathology60, 880–884
Concordance of HER2 status assessed on needle core biopsy and surgical specimens of invasive carcinoma of the breastAims: Human epidermal growth factor receptor 2 (HER2) status of invasive breast cancers is vital for selection of patients for trastuzumab treatment. This study aimed to assess the level of agreement...
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