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Die Immun-Checkpoint-Inhibition (ICI) hat die Systemtherapie metastasierter uroonkologischer Malignome deutlich verbessert. Mit der EMA-Zulassung (European Medicines Agency) der gegen „programmed cell death 1“ (PD-1) gerichteten Antikörper Nivolumab und Pembrolizumab sowie dem PD-L1-Antikörper („programmed cell death ligand 1“) Atezolizumab sind drei Substanzen in der Therapie des metastasierten Urothel-...
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