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Methods currently used for micro-array data classification aim to select a minimum subset of features, namely a predictor, that is necessary to construct a classifier of best accuracy. Although effective, they lack in facing the primary goal of domain experts that are interested in detecting different groups of biologically relevant markers. In this paper, we present and test a framework which aims...
Microarray data has been widely used to predict different disease condition. But the problem has been the high dimensionality of microarray data, because of very few samples compared to a huge number of genes. To tackle this necessity we have developed EVOL Optimer (Evolutionary Optimization). In our method we used both filter and wrapper based approach for gene selection. The original subsets are...
Microarray data contains thousands of genes which are used to evaluate expression level. However, most of them are not associated with cancer diseases and leads to the curse of dimensionality. The challenge based on microarray data is feature selection which searches for subsets of informative genes. At the moment, these techniques focus on filter and wrapper approaches to discover subsets of genes...
In the past decade, DNA microarray technologies have had a great impact on cancer genome research; this technology has been viewed as a promising approach in predicting cancer classes and prognosis outcomes. In this paper, we proposed two systematic methods which can predict cancer classification. By applying the genetic algorithm gene selection (GAGS) method in order to find an optimal information...
Microarray data are expected to be of significant help in the development of efficient cancer diagnoses and classification platforms. The main problem that needs to be addressed is the selection of a small subset of genes from the thousands of genes in the data that contributes to a cancer disease. This selection process is difficult due to the availability of a small number of samples compared to...
Gene expression data usually contains a large number of genes (several thousand or more) but a small number of samples (usually <100). Among all the genes, many are irrelevant, insignificant or redundant to the discriminant problem under investigation. Hence the identification of informative genes, which have the greatest power for classification, is of fundamental and practical importance to the...
Microarray technology has been widely applied to search for biomarkers of diseases, diagnose diseases and analyze gene regulatory network. Abundance of expression data from microarray experiments are processed by informatics tools, such as supporting vector machines (SVM), artificial neural network (ANN), and so on. These methods achieve good results in single dataset. Nevertheless, most analyses...
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