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The inside cover picture illustrates the impact of the different approaches for the development of asymmetric oxidative Mannich reactions to synthesize chiral β‐amino carbonyl compounds, very important building blocks in organic synthesis and in the pharmaceutical chemistry, which have been described in the last years. Details can be found in the review by J. R. Pedro, C. Vila and co‐workers. (J....
The asymmetric Mannich reaction is one of the most straightforward methodologies for the enantioselective synthesis of chiral amines. In general, asymmetric Mannich reactions involve the use of imines as electrophiles. However, in recent years, several asymmetric oxidative Mannich reactions have been reported using amines as electrophiles. This review provides an overview of these recent publications,...
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