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Purpose Casein kinase (CK) 2 activation has been implicated in the proliferation of various tumor types and resistance to chemotherapy. We investigated the mechanistic basis for the association between CK2 activation and paclitaxel resistance in a gastric cancer (GC). Experimental design CK2 expression was evaluated in 59 advanced GC patients treated with paclitaxel as the second-line therapy. The...
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