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The primary goal of neuroimaging in a first, unprovoked seizure is to identify a lesion that can explain the seizure. Secondarily, neuroimaging may be used to predict seizure recurrence and assist with the diagnosis of epilepsy. However, the events leading from a first seizure to epilepsy, with or without an identifiable epileptogenic lesion, are not well understood, and it is not always clear which...
Brain scanning methods were first applied in patients with epilepsy more than 30years ago. A very substantial literature now exists in this field, which is exponentially increasing. Contemporary neuroimaging studies in epilepsy reflect new concepts in the epilepsies, as well as current methodological developments. In particular, this area is emphasising the role of networks in epileptogenicity, the...
The purpose of this investigation was to examine the diffusion properties of cerebral white matter in children with recent onset epilepsy (n=19) compared to healthy controls (n=11). Subjects underwent DTI with quantification of mean diffusion (MD), fractional anisotropy (FA), axial diffusivity (D ax ) and radial diffusivity (D rad ) for regions of interest including anterior and posterior...
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