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The cross-dependency of noise level and photobleaching in microscopy was discussed in a previous work and an efficient compressed sensing (CS) method was proposed to simultaneously reduce the noise level and the photobleaching. Here we present an improved CS denoising framework for fluorescence microscopy images, exploiting Non-Local means filtering to merge multiple reconstructions. This framework...
Time-of-flight (TOF) PET scanners provide the potential for significantly improved signal-to-noise ratio (SNR) and lesion detectability in clinical PET. Therefore, it is likely that TOF will become the standard for clinical whole body PET in the near future. However, fully 3D TOF PET image reconstruction is a challenging task due to the huge data size. One solution to this problem is to rebin TOF...
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