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The human basal forebrain has been known to contain many neurons immunoreactive (ir) to tyrosine hydroxylase (TH; the first dopamine-synthesizing enzyme). We examined whether these neurons might contain aromatic l-amino acid decarboxylase (AADC; the second step dopamine-synthesizing enzyme) by dual labeling immunohistochemistry and confocal laser-scanning microscopy. Neurons dually-labeled for TH...
The presence of dopaminergic neurons in the rostral forebrain has long been uncertain though the existence of tyrosine-hydroxylase (TH)-containing cells has been known in the region. Using an antibody to dopamine (DA), we demonstrated neurons immunoreactive (ir) to DA in the rostroventral striatum of the Japanese monkey (Macaca fuscata). The DA-ir cells were found at the ventral margin of the rostral...
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