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The behavioral effects of crotoxin (CTX), the major component of Crotalus durissus terrificus venom, were studied in rats submitted to the open field, holeboard, and social interaction tests. CTX (100, 250, and 500 μg/kg, IP) was administered 2 h before the tests. In the open field, CTX reduced ambulation (250 μg/kg) and rearing (250 and 500 μg/kg) and increased grooming (100 and 250 μg/kg) and freezing...
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