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c‐Jun NH2‐terminal kinases (JNKs) are members of the mitogen‐activated protein kinase (MAPK) family that regulate multiple aspects of liver cell biology in the healthy and diseased liver. JNKs exert key functions in the control of proliferation, cell death, survival, and inflammation. Accordingly, JNKs have been implicated in the promotion of acetaminophen‐ and TNF‐induced liver injury, liver regeneration,...
The gut microbiota has recently emerged as a major player in many diseases inside and outside the gastrointestinal tract. Various types of liver diseases such as nonalcoholic fatty liver disease (NAFLD), alcoholic liver disease, and liver cirrhosis have recently been suggested to be closely associated with a profound dysbiosis. Clinical but especially preclinical experimental studies have suggested...
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