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Objective
To evaluate the biological effects of selective cyclooxygenase‐2 inhibition on prostate tissue in patients undergoing radical prostatectomy (RP).
Patients and Methods
Patients with localised prostate cancer were randomised to receive either celecoxib 400 mg twice daily or placebo for 4 weeks before RP. Specimens were analysed for levels of apoptosis, prostaglandins, and androgen receptor...
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